Raynaud’s Phenomenon by Fredrick M. Wigley Ariane L. Herrick & Nicholas A. Flavahan

Author:Fredrick M. Wigley, Ariane L. Herrick & Nicholas A. Flavahan
Language: eng
Format: epub
Publisher: Springer New York, New York, NY

Number of Fingers to Be Studied

Different investigators have studied different numbers of nailfolds (e.g. 10 nailfolds, 8 nailfolds and 1 nailfold [finger 4]). For example, ten fingers have been evaluated in the seminal study describing “normal” capillaroscopic appearances in a study population of 800 healthy subjects by using stereomicroscope [18]. On the other hand, in the screening of a patient with RP with the manual capillaroscopic techniques with qualitative assessment (see below), examination of eight fingers is usually recommended [6]. This is based on the fact that there may be a high variability in morphology between fingers in patients affected by a secondary RP. Of note, the thumbs are usually spared in secondary RP [19] and not evaluated.

Interestingly, it is noteworthy that preliminary study on semiautomatic nailfold capillaroscopy has recently demonstrated the ability through quantitative assessment (see below) to separate healthy controls and patients with primary RP from secondary RP due to SSc by evaluating only one finger (ring finger of nondominant hand) [13].

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